Jason Iles

Independent Researcher

Publications

Validation of a MALDI-TOF MS Method for SARS-CoV-2 Detection on the Bruker Biotyper and Nasopharyngeal Swabs: A Brazil—UK Collaborative Study

O. A. Lovison, R. Grigaite, F. Volpato, J. Iles, Jonathan Lacey, F. Barreto, Sai R. Pandiri, Lisiane da Luz R Balzan, V. Cantarelli, A. Barth, R. Iles, A. F. Martins

medRxiv 2023

ABSPDF

Degree of immunoglobulin kappa light chain glycosylation of anti-spike SARS CoV-2 antibodies correlates with COVID-19 severity.

R. Grigaite, J. Iles, S. Harding, R. Patel, G. Wallis, R. Iles

medRxiv 2023

ABS
Direct Detection of Glycated Human Serum Albumin and Hyperglycosylated IgG3 in Serum, by MALDI-ToF Mass Spectrometry, as a Predictor of COVID-19 Severity

Direct Detection of Glycated Human Serum Albumin and Hyperglycosylated IgG3 in Serum, by MALDI-ToF Mass Spectrometry, as a Predictor of COVID-19 Severity

R. Iles, J. Iles, Jonathan Lacey, Anna E. Gardiner, R. Zmuidinaite

Diagnostics 2022

ABSPDF
A How to Guide: Clinical Population Test Development and Authorization of MALDI-ToF Mass Spectrometry-Based Screening Tests for Viral Infections

A How to Guide: Clinical Population Test Development and Authorization of MALDI-ToF Mass Spectrometry-Based Screening Tests for Viral Infections

R. Iles, J. Iles, R. Zmuidinaite, M. Roberts

Viruses 2022

ABSPDF
SARS-CoV-2 Spike Protein Binding of Glycated Serum Albumin—Its Potential Role in the Pathogenesis of the COVID-19 Clinical Syndromes and Bias towards Individuals with Pre-Diabetes/Type 2 Diabetes and Metabolic Diseases

SARS-CoV-2 Spike Protein Binding of Glycated Serum Albumin—Its Potential Role in the Pathogenesis of the COVID-19 Clinical Syndromes and Bias towards Individuals with Pre-Diabetes/Type 2 Diabetes and Metabolic Diseases

J. Iles, R. Zmuidinaite, Christoph Sadée, Anna E. Gardiner, Jonathan Lacey, S. Harding, J. Ule, Debra Roblett, J. Heeney, H. Baxendale, R. Iles

International Journal of Molecular Sciences 2022

ABSPDF

Direct detection of humoral marker corelates of COVID-19, glycated HSA and hyperglycosylated IgG3, by MALDI-ToF mass spectrometry.

R. Iles, J. Iles, R. Zmuidinaite, A. Gardiner, J. Lacey, S. Harding, J. Heeney, D. Baxendale

medRxiv 2021

ABS

Determination of IgG1 and IgG3 SARS-CoV-2 Spike Protein and Nucleocapsid Binding—Who Is Binding Who and Why?

J. Iles, R. Zmuidinaite, Christoph Sadée, Anna E. Gardiner, J. Lacey, S. Harding, G. Wallis, Roshani Patel, Debra Roblett, J. Heeney, H. Baxendale, R. Iles

medRxiv 2021

ABSPDF

A clinical MALDI-ToF Mass spectrometry assay for SARS-CoV-2: Rational design and multi-disciplinary team work.

R. Iles, R. Zmuidinaite, J. Iles, George William Carnell, A. Sampson, J. Heeney

medRxiv 2020

ABSPDF

Non-invasive selection of optimal embryos immediately prior to embryo transfer using bioinfomatic analysis of spectral data following matrix assisted laser desorbtion/ionisation time of flight mass spectrometry

S. Butler, F. Sharara, J. Cooper, J. Iles, R. Zmuidinaite, G. Abdo, S. Keshavarz, R. Iles

ABSPDF
ArticleDevelopment of a clinical MALDI-ToF Mass spectrometry assay for SARS-CoV-

ArticleDevelopment of a clinical MALDI-ToF Mass spectrometry assay for SARS-CoV-

R. Iles, R. Zmuidinaite, J. Iles, George William Carnell, A. Sampson, J. Heeney